NFL Week 18 schedule: 49ers vs. Cardinals game date, time announced

The date has officially been set for the 49ers’ Week 18 matchup against the Arizona Cardinals.

San Francisco will conclude the 2022 regular season at Levi’s Stadium on Sunday at 1:25 p.m. PT.

The 49ers have a chance to clinch the NFC’s No. 1 playoff seed as they enter Week 18. That would require San Francisco (12-4) to beat Arizona and the New York Giants to beat the Philadelphia Eagles (13-3).

Meanwhile, the Eagles need a win or tie with the Giants to clinch the top seed and the NFC East. The Dallas Cowboys (12-4) are another team with a chance to steal the No. 1 seed, and they can do so by defeating the Washington Commanders in combination with losses by the 49ers and Eagles.

It’s no coincidence that the 49ers, Cowboys and Eagles will play their Week 18 games simultaneously, kicking off at 1:25 PM PT on Sunday.

The NFL has set the dates for Week 18 games after all playoff scenarios have been revealed. The Kansas City Chiefs and Las Vegas Raiders will play Saturday at 1:30 PM PT, followed by the Tennessee Titans vs. Jacksonville Jaguars at 5:15 PM PT. His remaining 14 games across the league will be played on Sunday.

Week 18 will see the 49ers face off against the Cardinals for the second time this season. San Francisco defeated Arizona easily, 38-10, at Mexico City’s Estadio Azteca on November 21. Jimmy Garoppolo threw for 228 yards and scored four touchdowns that night.

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The 49ers haven’t made a trip to Arizona this season, but hope to plan a trip to Glendale in February for Super Bowl LVII at State Farm Stadium.

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